Free Shipping Orders $40+
By Category




$89.00
You’re not alone - vaginal dryness, itching, pain during intimacy, and recurrent UTIs are common symptoms of perimenopause and postmenopause. SweetSpot Labs RX’s Estradiol Cream is here to help you feel at ease again. Our custom-blended, plant-based, bioidentical Estradiol cream is formulated in a gentle, vulva-friendly base that hydrates and revitalizes vaginal tissue.
Price includes online medical consultation and prescription.
Bioidentical, plant-based Estradiol: the natural estrogen your body needs
Clean, soothing formula: crafted with ingredients gentle enough for sensitive areas
Simply use the included applicator to apply a measured amount inside the vagina daily. One tube = 30 days of use. Follow your clinician’s directions for best results.
This product is custom compounded at 0.0125% estradiol per gram.
Estradiol vaginal cream is indicated in the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to low estrogen, symptoms of menopause including hot flashes, and to prevent osteoporosis.
Estradiol vaginal cream should not be used in women with any of the following conditions:
• Undiagnosed abnormal genital bleeding.
• Known, suspected, or history of cancer of the breast.
• Known or suspected estrogen-dependent neoplasia.
• Active deep vein thrombosis (DVT), pulmonary embolism (PE), or history of these conditions.
• Active arterial thromboembolic disease (for example, stroke or myocardial infarction) or a history of these conditions.
• Known anaphylactic reaction or angioedema to estradiol vaginal cream 0.01%.
• Known liver dysfunction or disease.
• Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders.
• Known or suspected pregnancy.
HRT medical guidelines for women with an intact uterus include estrogen plus progestin. Women who have had a hysterectomy may be prescribed estrogen alone.
Only a doctor can prescribe these medications. Discuss your options with your physician. Women with a history of certain cancers may not be advised to undergo HRT with estrogen, progesterone, or any other sex hormones.
Crafted by expert pharmacists and doctors in our Arizona-based compounding pharmacy.
This product is available by prescription only and is not intended to diagnose, treat, cure, or prevent any disease.

For many women, stress and anxiety are part of daily life, but when these feelings persist, they can take a toll on more than just your mood.
Dr. Marisa Messore, GYN, Menopause & Female Sexual Health Specialist, on Female Sexual Dysfunction
Dr. Marisa Messore, GYN, on Low Sex Drive in Women and Treatment Options